Posty supports the ability to microblog to Twitter, Jaiku, Pownce, Tumblr, FriendFeed and Identi.a simultaneously, much like Ping.fm. In the Adobe AIR app, you write your message on the right, select the networks you want to hit, and Posty submits them in parallel.
While I tend to use Posty simply for submitting, you can also catch up on your friends' timeline or the public timeline of each service, giving you a small window into the world of what's going on at Twitter, FriendFeed and the rest.
As Cesare lays out in a blog post today, the newest version adds support for direct messages for both Twitter and Identi.ca, support for favorites in both Twitter and Identi.ca, support for retweeting, and integrated URL shortening, using the http://is.gd engine.
I can DM directly from Posty now.
The application is still small in stature, and lacks some of the UI customizations seen in TweetDeck for example, but when it comes to usability, Posty just does its job well, and I'll keep using it, at least until TweetDeck integrates Identi.ca or FriendFeed, which would make things a lot more interesting.
You can download Posty here.